Professor Pierce Chow


MBBS, FRCSE, MMed (Surgery), FAMS, PhD

Professor and Program Director, Duke-NUS Medical School, Singapore

Senior Consultant, Department of Hepato-pancreato-biliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore


Prof Pierce Chow is Professor and Program Director at the Duke-NUS Medical School and Senior Consultant Surgeon at the National Cancer Centre Singapore (NCCS) and the Singapore General Hospital. He is concurrently a National Medical Research Council (NMRC) funded Senior Clinician-Scientist and was the founding President of the College of Clinician Scientists, Academy of Medicine Singapore.


Prof Chow was conferred the Chapter of Surgeon’s Gold Medal in the conjoint FRCSE/MMed examination in 1995, and after completing his surgical residency and PhD, he trained in liver transplantation with Professor Russell Strong in Australia. On top of his busy clinical practice in hepato-pancreato-biliary (HPB) surgery, Prof Chow has been very active in clinical and translational research in liver cancer.


Prof Chow co-founded the Asia-Pacific Hepatocellular Carcinoma (AHCC) Trials Group and has been the protocol chair of more than ten prospective multi-center clinical studies in liver cancer over the last 20 years. Pierce has led the multi-disciplinary NMRC TCR National Flagship Program in Liver Cancer since 2016 and the program has been successfully renewed in 2022 with the NMRC OF-LCG grant. In 2020, he was awarded an A*STAR IAF-ICP grant in collaboration with industry, to conduct a nation-wide 2000-patient cohort study to develop diagnostics for early detection of hepatocellular carcinoma (HCC) in high-risk patients. Subsequently
in 2021, he initiated a multi-national, investigator-initiated Phase II randomised clinical trial (STRATUM) fully supported by industry to compare the safety and efficacy of a novel combinatorial treatment for intermediate HCC patients. Pierce is also a faculty member at the Genome Institute of Singapore and the SingHealth Duke-NUS Global Health Institute, and Research Director at the Institute of Cell and Molecular Biology Singapore. Prof Chow was conferred the NMRC National Outstanding Clinician Scientist Award in 2012 for improving clinical outcomes with his research on Liver Cancer.


Prof Chow is also very active in medical education and was the inaugural course director of the Human Structure and Function course at the MD program of the Duke-NUS Medical School Singapore (2007 – 19). He is also the inaugural Program Director of the PhD Program in Clinical and Translational Sciences at Duke-NUS (2018 – current). Prof Chow is on the faculty of the Surgery Residency Program at SingHealth and continues to be Course Director for Advanced Trauma Life Support (ATLS) courses.